ea0049gp209 | Thyroid 2 | ECE2017
Zake Tatjana
, Skuja Sandra
, Kalere Ieva
, Konrade Ilze
, Groma Valerija
Introduction: Recently, Th17 cells and their cytokines were identified to play an important role in the pathogenesis of thyroid autoimmunity. IL-23, produced by antigen presenting cells, is required for survival and differentiation of Th17 cells, and is known to guide T cells toward the Th17 phenotype. Its serum levels are increased in several autoimmune diseases, including Hashimotos thyroiditis (HT), however, the expression level of IL-23 within thyroid tissue assessed...